one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the remedy of a number of myeloma. Its synthesis or study is essential for guaranteeing the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the procedure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound within the synthesis of imatinib, a drug that targets precise varieties of cancer, which includes Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers including breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the output approach and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to treat breast cancer, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the cure of breast cancer. Many intermediates help 7-dihydro-4-oxo-1H-pymol[2 in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment of colorectal most cancers and modest mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is associated with the synthesis of adamantane derivatives, which have various purposes, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-4 to manage CAS NO. 314771-76-1 blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of varied gluconic acid derivatives, that are Employed in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilized to control type two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).